Cumberland River Cruise

Cruise from Nashville to St. Louis, following the Cumberland and Mississippi Rivers on a route of adventure and captivating history. Admire the picturesque scenery of America's Heartland, including the Kentucky Lakes and rolling landscape of 170,000 acres of protected forest.

Enjoy guided excursions to the legendary Grand Ole Opry in Nashville, the National Quilt Museum in Paducah, and the Trail of Tears State Park in Cape Girardeau. Travel to Dover for a private tour of the historic battleground where Ulysses S. Grant won his first major Union victory.

Experience a relaxing day cruising Lake Barkley and admire panoramic views from the comfort of your private balcony. In the evening, listen to the finest Country, Jazz, and Rock n’ Roll music performed by our acclaimed onboard entertainers.

Ask about our Current Savings and our Complimentary Pre-cruise Packages which include a premium hotel stay and transportation to the ship.

US River Cruise Guide

The New 2020-2021 Cruise Guide is now available.

Free Cruise Guide

Call Toll-Free Today!

7 days a week*

Cruise Itinerary

Ports of Call
Nashville, TN
Clarksville, TN
Dover, TN
Cruising Lake Barkley
Paducah, KY
Cape Girardeau, MO
Chester, IL
St. Louis, MO

Cumberland River Cruise

On your 8-day cruise from Nashville to St. Louis, enjoy the migratory songbirds, woodpeckers, and red-tailed hawks that make the Cumberland River cruise come alive. Throughout your journey, visit historic sites, vibrant artist communities, and beautiful state parks. 

Ports of Call

  • Complimentary Package
  • Nashville, TN
  • Clarksville, TN
  • Dover, TN
  • Paducah, KY
  • Cape Girardeau, MO
  • Chester, IL
  • St. Louis, MO

Day by Day

Reverse itineraries available. Please contact your Cruise Specialist for more information. Excursions subject to change.

Day by Day Thumbnail

Complimentary Package

Each Mississippi itinerary comes complete with a Complimentary Pre-Cruise Package, providing you with a seamless way to board the ship and explore the local area. Arrive the day before your scheduled cruise date and American Cruise Lines will handle the rest. The package includes a premium hotel stay, where you can enjoy the city at your leisure. On the morning of the cruise, meet in the hotel lobby after breakfast and we will transport you to the ship to begin your cruise. All luggage will be brought directly from the hotel and placed in your stateroom aboard the ship.

Pre-Cruise Packages must be reserved at least 30 days before your cruise date.

Day by Day Thumbnail

Day 1
Nashville, TN

From the legendary Grand Ole Opry to the Country Music Hall of Fame, Nashville is the official headquarters of country music. The lively streets are lined with art galleries and unique shops that welcome you at every turn. Consider touring The Hermitage, the home of President Andrew Jackson; the gardens of Cheekwood where more than 55,000 tulips bloom in the spring, or Gaylord Opryland's nine acres of indoor gardens and waterfalls.


Nashville Experience - Complimentary Excursion

Enjoy a narrated tour of Historic Downtown Nashville, including the famous Country Music Hall of Fame Museum, Honky Tonk Row, Bicentennial Park, and State Capitol. Traveling west of the city, visit the only full-size replica of the Parthenon, nicknamed “The Athens of the South.” 

Please Note: This tour is only offered on cruises ending in Nashville, TN.


Ryman Auditorium

Learn the fascinating story of the Ryman Auditorium with a guided backstage tour! Constructed in 1880, Thomas G. Ryman built this theater, originally named The Union Gospel Tabernacle, for evangelist Reverend Sam Jones so that his inspiring words could be clearly heard by all. After Ryman’s passing in 1904, the theater name was changed to Ryman Auditorium to honor the man who created this historic landmark. Today, the Ryman Auditorium is associated with country music legends and inspiring artists striving to make a name for themselves.

Please Note: This tour is only offered on cruises ending in Nashville, TN.


Grand Ole Opry Show - Complimentary Excursion

Enjoy live country music at its best with a visit to the Grand Ole Opry. The evening show will begin at 7:00 pm, featuring up and coming country artists, as well as musical groups that have been Opry Members for years.  

Day by Day Thumbnail

Day 2
Clarksville, TN

Discover Clarksville, named for General George Rogers Clark, a frontier fighter, Revolutionary War hero, and brother of William Clark of the Lewis and Clark Expedition. As you explore the city led by our local guides, learn how Clarksville rose as a major tobacco port during the 1800s. Tour the Don F. Pratt Memorial Museum which houses military memorabilia, or Dunbar Cave, one of the largest caves in the county.


Fort Defiance - Complimentary Excursion

Beginning in the late 18th century, Fort Defiance was a central hub for trading goods and settlement for both the Native Americans and Europeans. During the Civil War, the Fort became a base for the Confederate Troops. However in 1862, the fort was captured by Union Troops and stayed under their command for the remainder of the war. The grounds have been well preserved since the war ended, so you will truly capture the true essence of its history.

american cruises

Customs House Museum & Cultural Center - Complimentary Excursion

Designed by William Aicken and commissioned by President Grover Cleveland, this building, constructed in 1898, once housed a U.S. Post Office and Customs House for the flourishing tobacco trade. Now a museum, this architecturally fascinating structure is among the most photographed buildings in Tennessee.  Explore its featured exhibits, fine art galleries, and sculpture garden. 

Day by Day Thumbnail

Day 3
Dover, TN

The small town of Dover is a historic treasure as well as a place of scenic beauty. Home to Fort Donelson National Park, the town played a pivot role in the Civil War as the site of a major Union victory. Within Dover is the Cross Creeks National Wildlife Refuge, an over 8,000-acre habitat of waterfowl and plant life, as well as the Land Between Lakes National Recreation Area. 

small ship cruising

Fort Donelson National Military Park - Complimentary Excursion

Once the gateway to the Confederate Heartland, the Battle of Fort Donelson became a key victory for Ulysses Grant and Union forces. Enjoy a warm welcome at the visitor’s center by tour guides who are eager to share their knowledge. After a short introductory film, tour the grounds of the fort, surrender site, and National Cemetery while learning about the military strategies employed by each side and how the Union victory impacted the entire Civil War.

Day by Day Thumbnail

Day 4
Cruising Lake Barkley

Located in Western Kentucky, explore Lake Barkley on a relaxing day of cruising. Take in the view of the beautiful shoreline from one of the Queen of the Mississippi's spacious, comfortable lounges, while enjoying the company of fellow guests.

Day by Day Thumbnail

Day 5
Paducah, KY

Founded by William Clark (of Lewis and Clark), Paducah is known as a National Heritage Destination with many talented culinary artists, painters, potters, and jewelers creating and displaying their works there. Also known as “Quilt City,” there is plenty to do in Paducah from shopping to visiting one the many fine museums, to participating in a hands-on creative workshop at a local art gallery.

small ship cruising

Paducah City Excursion & National Quilt Museum

Let our local guide take you through the quaint city of Paducah. This tour has been carefully divided into three distinct sections to make sure you experience all that Paducah has to offer. First, tour the downtown as our local expert guide points out the areas’ many historical sites. Then, take a leisurely stroll along the riverfront where you will witness more than 50 life-sized panoramic murals depicting elements of Paducah’s past. End the tour at the National Quilt Museum, the world's largest museum devoted to quilt and fiber art.

small ship cruising

River Discovery Center

Paducah’s location at the confluence of the Ohio and Tennessee Rivers makes it unique.  The city is home to some of the nation’s largest barge and towing companies. At the River Discovery Center, learn all about the inland waterways and the impact they have on the daily lives of local residents. You can be a captain and choose your vessel type in the state-of-the-art boat simulator, as well as explore and learn about the history, environments, culture, and economy of these rivers through interactive exhibits. 

Day by Day Thumbnail

Day 6
Cape Girardeau, MO

Just thirty miles from the confluence of the Mississippi and Ohio Rivers, this river town became an important trading post in the 1800s. Visited by Lewis and Clark, Cape Girardeau has a storied history that resonates throughout the town, from the Trail of Tears State Park to the many outdoor murals reflecting the area's rich history.


Cape Girardeau Experience - Complimentary Excursion

Join a local guide on a narrated tour of Cape Girardeau and stop at the Crisp Museum. A part of the River Campus of Southeast Missouri State University, the museum features fine art exhibitions, prehistoric Native American artifacts, one of the largest collections of ceramic conch shell effigies in North America, and interpretive regional history displays. Upon arrival, watch a wonderful introductory film, followed by a museum tour, where you can view a life-sized replica of a Native American dwelling.

small ship cruising

Trail of Tears State Park

The evening before arriving in Cape Girardeau, your onboard historian will paint a vivid picture of the Cherokee peoples' crossing of the Mississippi River to land in present-day Oklahoma. The forced march became known by the Cherokee people as the Trail of Tears due to its devastating effects.

Memorializing this event is the Trail of Tears State Park. Led by our expert guide, explore the interpretive center, which houses a series of panels, paintings, maps, and other memorabilia depicting the Cherokees’ tragic crossing of the Mississippi River.

Day by Day Thumbnail

Day 7
Chester, IL

Located on a bluff overlooking the Mississippi River, Chester is a beautiful region of Illinois with a diverse and storied history. Chester is home to Popeye's creator Elzie C. Segar. You may see the sailor man's likeness in the town's own six-foot-tall bronze metal statue.

american cruises

Popeye Character Trail - Complimentary Excursion

Located on the scenic bluffs of the Mississippi River, Chester is best known as “The City of Popeye,” as it is the birthplace of his creator, Elzie Segar. Tour this quaint city with our local guide who will share stories of the people and places of this little corner of America. Shop at Spinach Can Collectibles in Gazebo Park for Popeye-inspired gifts and take a picture with the famous Popeye statue. Visit the Cohen Memorial Home whose bright blue windows even caught the attention of Mark Twain as he traveled the Mississippi.

Day by Day Thumbnail

Day 8
St. Louis, MO

This “Gateway to the West” was the epicenter for exploration following the Louisiana Purchase of 1803. The largest city on our cruise, St. Louis now has a distinct metropolitan culture. Take the elevator to the top of the Gateway Arch, which stands 630 feet over the Mississippi River.


Missouri History Museum

Enjoy a guided tour through two of the museum’s most popular exhibits; The 1904 World’s Fair: Looking Back at Looking Forward, an event that attracted over 200,000 visitors to the opening day, and Seeking St. Louis, delve into the history of the Gateway City from its founding through the new millennium.

Note: This excursion is only offered on cruises ending in St. Louis, MO and on the Complete Mississippi and Grand Heartland itineraries.

Small Ship Cruising

Discover St. Louis - Complimentary Excursion

Enjoy a narrated tour of downtown St. Louis, the riverfront, Citygarden, and the historic neighborhoods of Soulard and Lafayette Square. Delight in a visit to St. Louis' 1,371 acre Forest Park, known as a natural oasis in an urban environment. Stop at the Cathedral Basilica, where you explore the interior if this stunning church which rivals the cathedrals in Rome, Italy.

Note: This excursion is only offered on select cruises ending in St. Louis, MO and on the Complete Mississippi and Grand Heartland itineraries.


On this 8-day cruise along the Mississippi and Cumberland Rivers, visit historic sites, partake in engaging onboard enrichment programs, and witness stunning scenery. With majestic mountaintops and lush forest as a backdrop, the river views are nothing short of breathtaking.

Your Cruise Includes

Queen of the Mississippi

Built in 2015, Queen of the Mississippi offers an authentic paddlewheeler experience with all the comforts of home.

Guests can enjoy large staterooms with private balconies, hotel-style bathrooms, and complimentary room service. Experience breathtaking scenery from the privacy of your stateroom as the Queen of the Mississippi makes its way down the legendary river. 

Click a Category

Owner's Suite


At a generous up to 445 sq. ft., the Owner Suites of Queen of the Mississippi offer the finest accommodations with unsurpassed views of the Mississippi River. With a spacious seating area and full-size bathrooms, each suite is a private sanctuary where you can unwind after a day of exploration in the tasteful comfort of your surroundings. Each of these suites features large sliding glass doors leading out to a private balcony, where you can enjoy the ever-changing scenery. Every modern amenity is at your fingertips, along with a desk, and spacious seating area.

AAM (Private Balcony)


Located on the top deck, these spacious staterooms feature scenic views of the passing landscape. At 328 sq. ft., you will enjoy all of the modern comforts that are expected of a premium hotel. These staterooms also offer full-size bathrooms and a walk-out private balcony where the grandness of the Mississippi can be appreciated.

AAC (Private Balcony)


Our AAC staterooms are conveniently located on the fourth deck and at 304 sq. ft. offer all of the comforts of a fine hotel. Complete with a private balcony and floor-to-ceiling sliding glass doors, these staterooms provide spectacular panoramic views of the Mississippi River and the surrounding landscape. 

AAL (Private Balcony)


AAL staterooms can be found on the third deck of the Queen of the Mississippi. Enjoy a luxurious 304 sq. ft. of living space that is equipped with plush seating, a full-size bathroom, and a private balcony with large sliding glass doors that offer great views of the Mississippi scenery. 

AAR (Private Balcony)


AAR staterooms can be found on the second deck of the Queen of the Mississippi. Enjoy a luxurious 304 sq. ft. of living space that is equipped with a full-size bathroom and a large private balcony with sliding glass doors.  



These 290 sq ft staterooms offer exceptional comfort and a relaxing living area. Featuring a large opening picture window, all are equipped with modern amenities, full-size bathrooms, and closet space.

Single (Private Balcony)


Perfect for the solo traveler, our Single staterooms offer all of the amenities you expect from a fine hotel. At 230 sq. ft., these staterooms have spacious bathrooms and large sliding glass doors that lead to a private balcony.



A comfortable getaway, our Single staterooms offer individuals a spacious room with convenient amenities. At 203 sq. ft., all have interior entrances and large viewing windows where the sights of the Mississippi can be enjoyed.

Queen of the Mississippi Deck Plan


Nashville Country & Blues Cruise

Blues and Country music are distinctly American, with deep roots on the banks of the Mississippi River. This theme cruise explores Nashville, known as "Music City,” home to the Country Music Hall of Fame and Museum, the Grand Ole Opry, and the Johnny Cash Museum. The second largest city in Tennessee, Nashville maintains a vibrant music scene with a number of clubs, honky-tonk bars, and studios that continue the tradition of this city's musical heritage. St. Louis is another important stop on this musical journey. Synonymous with the blues, St. Louis has its own style and genre referred to as the "St. Louis Blues." 


More Less

Reserve Cruise

Fall Foliage Cruise

Enjoy the splendor of autumn along the Cumberland River. Enjoy the vivid fall colors of this scenic landscape during peak foliage season.

With majestic mountaintops and lush forest as a backdrop, the lake shore views during this time of year are nothing short of breathtaking.Visit vibrant artist communities, beautiful state parks, and historic sites such as the legendary Grand Ole Opry.

More Less

Reserve Cruise

Cruise Date



Load More

* Prices displayed are per person based on double occupancy.

See Our Other Mississippi River Cruises

View Itineraries ›

Save up to
Per Stateroom

Save On Select Cruises

Book your cruise and save.
Call a Cruise Specialist to learn about our current offers.
Call 800.460.4518 Reservations office open 7 days a week


The American Cruise Lines Difference

Coffee, mimosas, and a yellow rose on a serving tray placed on a bed
First-Class Staterooms
Lobster-tails, asparagus, and lemon
Delicious Cuisine
Housekeeping placing folded white towels and blue flowers on a white bed
Gracious Service
Nightly Entertainment